| 摘要 |
The invention relates to compounds of formula (1), wherein X, Y, Z, R1, R2, R3, R4, R5, R7, R8, R11, m and n have the meaning cited in Claim 1, and to their physiologically acceptable salts. Said compounds can be used as integrin inhibitors, specially for prophylaxis and treatment of circulatory diseases, thrombosis, infarcts, coronary heart diseases, arteriosclerosis, osteoporosis, pathological symptoms sustained or propagated by angiogenesis and in tumor therapy.
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| 申请人 |
MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG |
发明人 |
DIEFENBACH, BEATE;RIPPMANN, FRIEDRICH;WIESNER, MATTHIAS;RADDATZ, PETER;GOODMAN, SIMON L.;MARZ, JOACHIM |
