发明名称 |
BENZODIOXANE DERIVATIVES AND USES THEREOF |
摘要 |
<p>Compounds are described herein which are agonists or partial agonists of the 2C subtype of brain serotonin receptors. The compounds have the formula I: or pharmaceutically acceptable salts thereof, wherein each of A, R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>a</SUP>, R<SUP>b</SUP>, R<SUP>c</SUP>, R<SUP>d</SUP>, R<SUP>e</SUP>, R<SUP>x</SUP>, R<SUP>y</SUP>, m, n and each == group are as defined herein. Such compounds, and compositions thereof, are useful for treating a variety of central nervous system disorders such as schizophrenia.</p> |
申请公布号 |
WO2008052086(A1) |
申请公布日期 |
2008.05.02 |
申请号 |
WO2007US82450 |
申请日期 |
2007.10.24 |
申请人 |
WYETH;STACK, GARY, PAUL;DEMAIO, WILLIAM;ERVE, JOHN, CHUCK, LEM;VISHWANATHAN, KARTHICK;WANG, JIANYAO;VASHISHTHA, SARVESH |
发明人 |
STACK, GARY, PAUL;DEMAIO, WILLIAM;ERVE, JOHN, CHUCK, LEM;VISHWANATHAN, KARTHICK;WANG, JIANYAO;VASHISHTHA, SARVESH |
分类号 |
C07D319/20;A61K31/357;A61P25/18 |
主分类号 |
C07D319/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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