PIPERIDYL-PROPANE-THIOL CCR3 MODULATORS

摘要

One object of the present invention are novel substituted piperidyl-propa ne-thiols of the formula (1), wherein R1, R2, R3 and R4 are defined as below . Another object of the present invention is to provide agonists or antagoni sts of CCR-3, or pharmaceutically acceptable salts thereof, more particularl y to provide pharmaceutical compositions comprising a pharmaceutically accep table carrier and a therapeutically effective amount of at least one of the compounds of the present invention or a pharmaceutically acceptable salt the reof.