发明名称 BENZOYL AMINO HETEROCYCLYL COMPOUNDS AS GLUCOKINASE (GLK) ACTIVATORS
摘要 <p>The invention relates to a novel group of compounds of Formula (I) or a salt thereof: wherein R&lt;SUP&gt;1&lt;/SUP&gt;, R&lt;SUP&gt;2&lt;/SUP&gt;, R&lt;SUP&gt;3&lt;/SUP&gt;, n, A and HET-1 are as described in the specification, which may be useful in the treatment or prevention of a disease or medical condition mediated through glucokinase (GLK) such as type 2 diabetes. The invention also relates to pharmaceutical compositions comprising said compounds, methods of treatment of diseases mediated by GLK using said compounds and methods for preparing compounds of Formula (I).</p>
申请公布号 WO2008050117(A1) 申请公布日期 2008.05.02
申请号 WO2007GB04057 申请日期 2007.10.25
申请人 ASTRAZENECA AB;ASTRAZENECA UK LIMITED;MARTIN, NATHANIEL, GEORGE;MCKERRECHER, DARREN;PIKE, KURT, GORDON;WARING, MICHAEL, JAMES 发明人 MARTIN, NATHANIEL, GEORGE;MCKERRECHER, DARREN;PIKE, KURT, GORDON;WARING, MICHAEL, JAMES
分类号 C07D241/24;A61K31/4439;A61K31/497;A61P3/00;C07D401/12;C07D403/12 主分类号 C07D241/24
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