USE OF (METH)ACRYLATE COPOLYMERS IN SLOW-RELEASE PHARMACEUTICAL FORMS FOR REDUCING THE INFLUENCE OF ETHANOL ON ACTIVE INGREDIENT RELEASE
摘要
The invention relates to the use of (meth)acrylate copolymers which are insoluble in gastric juice in oral slow-release pharmaceutical forms to form a matrix for the contained active ingredient to reduce the effect of increasing or decreasing the rate of active ingredient release through the influence of ethanol under in vitro conditions.
申请公布号
WO2008049657(A2)
申请公布日期
2008.05.02
申请号
WO2007EP58100
申请日期
2007.08.06
申请人
EVONIK ROEHM GMBH
发明人
PETEREIT, HANS-ULRICH;SKALSKY, BRIGITTE;GALLARDO, DIEGO;ASSMUS, MANFRED;GRYCZKE, ANDREAS;WEISBROD, WOLFGANG;HOFMANN, FELIX;BAER, HANS