AMINO ACID-MODIFIED POLYPEPTIDE

摘要

PROBLEM TO BE SOLVED: To provide a new method of amino acid analog uptake with cells.

SOLUTION: The uptake of some kinds of amino acid analog into polypeptide produced by cells usually giving no polypeptide containing amino acid analog is attained by exposing cells to a growth medium containing the amino acid analog. The rate of the uptake is controlled by adjusting amino acid analog concentration in the medium and/or adjusting the osmotic pressure of the medium. The uptake enables change and study of chemical and physical features of the polypeptide.

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