发明名称 |
Development of Mammalian Genome Modification Technique Using Retrotransposon |
摘要 |
To comprehensively modify genome, it is intended to develop a transposition system of the copy and paste type which has an improved efficiency. This object has been achieved by the finding that an LTR retrotransposon is partly usable in a transposition system. Namely, a technique of efficiently transferring a foreign gene into a cell by using a transposon. More specifically speaking, a complete IPA element and a functional promoter sequence are found out. It is clarified that, without a combination of them, a retrotransposon cannot exert its function.
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申请公布号 |
US2008104723(A1) |
申请公布日期 |
2008.05.01 |
申请号 |
US20040579936 |
申请日期 |
2004.11.19 |
申请人 |
OSAKA INDUSTRIAL PROMOJTION ORGANIZATION C/O MYDOM;NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES |
发明人 |
TAKEDA JUNJI;HORIE HYOJI;YUSA KOSUKE;ISHIHARA HIROSHI |
分类号 |
A01K67/00;A01K67/027;C07H21/04;C12N15/09;C12N15/867;C12N15/87;C12Q1/02;C12Q1/68 |
主分类号 |
A01K67/00 |
代理机构 |
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地址 |
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