THIADIAZOLE-SUBSTITUTED COUMARIN DERIVATIVE AND USE OF THE SAME AS LEUCOTRIENE BIOSYNTHESIS INHIBITOR

摘要

PROBLEM TO BE SOLVED: To provide a treating agent of arteriosclerosis, a treating agent of asthma, a treating agent of allergy, an anti-inflammatory agent and a cell-protecting agent. SOLUTION: This leucotriene biosynthesis inhibitor is compound (I) [wherein, X is O or S; Y is O, S-NR6-CHR7or -NR8-C(O)-; and A is a 5-membered aromatic heterocyclic ring, a 6-membered aromatic heterocyclic ring, naphthalene, a heterocyclic two ring type aromatic ring system, phenyl or benzyl]. COPYRIGHT: (C)2008,JPO&INPIT