| 摘要 |
PROBLEM TO BE SOLVED: To provide a new compound which inhibits the production of an amiloid beta (Aβ) and an Aβproduction preventive agent using the same. SOLUTION: The compound is represented by formula (I): wherein Ar<SB>1</SB>represents an imidazolyl group optionally substituted by one to three substituents; Ar<SB>2</SB>represents a pyridinyl, pyrimidinyl, or phenyl group optionally substituted by one to three substituents; X<SB>1</SB>represents (1) -C≡C- or (2) an optionally substituted double bond, etc.; and R<SP>1</SP>and R<SP>2</SP>each represent an optionally substituted 1-6C alkyl, 3-8C cycloalkyl, etc. In addition, a pharmacologically acceptable salt of the compound and the use as a medicine are provided. COPYRIGHT: (C)2008,JPO&INPIT
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