| 摘要 |
[Object] To provide a pharmaceutical composition which is excellent as a medicament for prevention or treatment of diseases relating to immune action such as autoimmune diseases. [Means for Solution] A pharmaceutical composition comprising
1 or 2 or more selected from PPAR regulators and
1 or 2 or more selected from the group consisting of amino alcohol derivatives of the general formula (I):
[wherein
R 1 and R 2 are the same or different, and each represents a hydrogen atom or the like; R 3 represents a C1-C6 alkyl group or a hydroxymethyl group; R 4 represents a hydrogen atom, a C1-C6 alkyl group or the like; R 5 represents a phenyl group substituted with 1 to 3 substituents selected from the group consisting of a hydrogen atom, a halogen atom, a cyano group, a C1-C6 alkyl group or the like; X represents a vinylene group (CH=CH group), an oxygen atom or the like; Y represents a single bond, an oxygen atom or the like; Z represents a single bond, a C1-C8 alkylene group or the like; n represents an integer of 2 or 3]; and
pharmacologically acceptable salt thereof.
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