| 发明名称 |
TRICYCLIC INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE |
| 摘要 |
<p>The invention relates to compounds of formula (I). The said compounds of the formula (I) are poly-(ADP-ribosyl)transferase(PARP) inhibitors to be used as therapeutics in the treatment of cancer and the amelioration of the effects of stroke, head trauma and neurodegenerative diseases. As cancer therapeutics, the claimed compounds may be used, e.g., in combination with cytotoxic agents and/or radiation.</p> |
| 申请公布号 |
RO121778(B1) |
申请公布日期 |
2008.04.30 |
| 申请号 |
RO20010000795 |
申请日期 |
2000.01.10 |
| 申请人 |
AGOURON PHARMACEUTICALS, INC.;CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED |
发明人 |
WEBBER STEPHEN EVAN;CANAN-KOCH STACIE, S.;TIKHE JAYASHREE GIRISH;THORESEN LARS HENRIK |
| 分类号 |
C07D471/06;A61K;A61K31/437;A61K31/4375;A61K31/55;A61K31/551;A61P;A61P3/10;A61P9/10;A61P25/28;A61P29/00;A61P35/00;A61P43/00;C07D;C07D209/00;C07D221/00;C07D223/00;C07D243/00;C07D487/00;C07D487/06;C07D519/00 |
主分类号 |
C07D471/06 |
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