摘要 |
Compounds and methods for treating diseases mediated by a P2X 3 and/or a P2X 2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of formula (I)
or a pharmaceutically acceptable salt, solvate or prodrug thereof, wherein D, X, Y, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and R 8 are as defined herein, |
申请人 |
F. HOFFMANN-LA ROCHE AG. |
发明人 |
CARTER, DAVID SCOTT;HAWLEY, RONALD CHARLES;PARISH, DANIEL WARREN;JAHANGIR, ALAM;DILLON, MICHAEL PATRICK;LIN, CLARA JEOU JEN;BROKA, CHRIS ALLEN |