发明名称 Diaminotriazoles useful as inhibitors of protein kinases
摘要 Disclosed is a compound of formula (II) or (II'), wherein R1 is hydrogen, R2 is a substituted phenyl or a substituted 3-7-membered saturated or partially unsaturated monocyclic ring having 0-3 heteroatoms selected from nitrogen, oxygen, or sulfur, or an 8-12-membered saturated or partially unsaturated bicyclic ring system having 0-5 heteroatoms independently selected from nitrogen, oxygen or sulfur, and the remaining substituents are as defined in the specification. The compounds are useful as inhibitors of protein kinases.
申请公布号 NZ540662(A) 申请公布日期 2008.04.30
申请号 NZ20030540662 申请日期 2003.11.17
申请人 VERTEX PHARMACEUTICALS INCORPORATED 发明人 PIERCE, ALBERT C;ARNOST, MICHAEL;DAVIES, ROBERT J;FORSTER, CORNELIA J;GALULLO, VINCENT;GREY, RONALD;LEDEBOER, MARK;TIAN, SHI-KAI;XU, JINWANG;BINCH, HAYLEY;LEDFORD, BRIAN;MESSERSMITH, DAVID;NANTHAKUMAR, SUGANTHI;JAYARAJ, ANDREW;WANG, JIAN;SALITURO, FRANCESCO G;HENKEL, GREG
分类号 A61K31/4196;A61K31/5377;A61K31/541;A61K31/55;C07D249/10;C07D249/14;C07D401/04;C07D401/12;C07D401/14;C07D403/04;C07D403/10;C07D403/12;C07D403/14;C07D405/04;C07D405/06;C07D405/12;C07D405/14;C07D413/02;C07D417/02;C07D417/04;C07D417/12;C07D417/14;C07D471/14;C07D487/04;C07D495/04;(IPC1-7):A61K31/41;C07D498/04;C07D513/04 主分类号 A61K31/4196
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