发明名称 |
MULTI-PHASE CONTRACEPTIVE PREPARATION BASED ON A ESTROGEN |
摘要 |
The multiphase preparation having higher contraceptive safety and reduced side effects is based on a combination of a natural oestrogen with dienogest or drospirenone. The multiphase preparation is characterized by a first phase consisting of 2 daily dose units of 3 mg of oestradiol valerate, a second phase consisting of 2 groups of daily dose units, wherein a first group is formed by 5 daily dose units each containing a combination of 2 mg of oestradiol valerate and at least two or three times an ovulation-inhibitory dose of dienogest or drospirenone and a second group is formed by 17 daily dose units each containing a combination of 2 mg of oestradiol valerate and at least three or four times the ovulation-inhibitory dose of dienogest or drospirenone, a third phase consisting of 2 daily dose units of 1 mg of oestradiol valerate, and a further phase consisting of 2 daily dose units of pharmaceutically acceptable placebo. |
申请公布号 |
ZA200609594(B) |
申请公布日期 |
2008.04.30 |
申请号 |
ZA20060009594 |
申请日期 |
2006.11.17 |
申请人 |
BAYER INTELLECTUAL PROPERTY GMBH |
发明人 |
ENDRIKAT JAN;DUSTERBERG BERND |
分类号 |
A61K;A61K31/00;A61K31/56;A61K31/57;A61P |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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