INDOLE DERIVATIVE HAVING PGD2 RECEPTOR ANTAGONIST ACTIVITY

摘要

The present invention creates an indole derivative having DP receptor antagonistic activity and a pharmaceutical composition comprising the said compound as an active ingredient, and further a therapeutic agent for treating allergic diseases. A compound of the generic formula (I)
wherein the ring A is an aromatic carbocyclic ring etc.; the ring B is a 3- to 8-membered nitrogen-containing non-aromatic heterocyclic ring etc.;R 1 , R 2 , R 3 , R 4 and R 5 are independently a hydrogen atom or a halogen atom etc.; R 6 is C2-C4 alkyloxy etc.; R 7 is independently a halogen atom etc.; R 8 is independently C1-C4 alkyl etc.; R 9 is carboxy etc.; Y is a single bond etc.; M is sulfonyl etc.; L 1 , L 2 and L 3 are a single bond or alkylene optionally containing one or two heteroatoms etc.; n is 0 etc.; q is 0 etc.;
a pharmaceutically acceptable salt or hydrate thereof.