| 摘要 |
<p>1-Isopropyl-4-methyl-cyclohexane compounds (I) or their mixtures and stereoisomers (enantiomers or diastereomers), are new. 1-Isopropyl-4-methyl-cyclohexane compounds of formula (I) or their mixtures and their stereoisomers (enantiomers or diastereomers), are new. Either R 1>, R 2>H or cyclic, optionally saturated, optionally one or more substituted 1-5C hydrocarbon; or R 1>R 2> connected over a bond or by O, S or NH : 3-7-membered ring; either R 3>, R 4>H, cyclic, optionally saturated 1-10C-hydrocarbon or 1-10C-hydrocarbon substituted by R 5>X; or R 3>R 4> connected over a bond or -O-, -S or -NH- : 3-7-membered heterocyclic ring; X : O, S or -NR 6>; and R 5>, R 6>H or cyclic, optionally saturated 1-5C-hydrocarbon. Independent claims are included for: (1) a mixture comprising (I) or its mixture, one or more further materials with physiological cooling effect, and optionally causing flavorful effect, one or more aroma materials without physiological cooling effect and/or one or more trigeminal or mouthwash effective materials without physiological cooling effect; (2) a therapeutic or non-therapeutic procedure for obtaining a physiological cooling effect on the skin and/or mucous membrane comprising applying (I), mixture or preparation on the skin and/or mucous membrane; and (3) the preparation of (I). [Image].</p> |
