Provided is an iontophoresis device. In the device, a doping layer is provided on an electrode in a working electrode structure or non-working electrode structure of the device. The doping layer comprises a substance which can cause an electrochemical reaction by doping or dedoping of an ion (e.g., an ion of a conductive polymer). The device can prevent or at least reduce the generation of a gas or undesirable ion which may be caused by the electrode reaction in an electrode structure or the denaturation of a medicinal substance which may be caused by any chemical reaction during energization of the device.
