发明名称 Method for the extraction of polyphenols and uses thereof
摘要 <p>Extraction of polyphenol from Cranberry juice (Vaccinium macrocarpon), comprise eliminating inert substances contained in the juice by diluting concentrated juice in water; fixing polyphenolic substances on a polymer adsorbing materials; rinsing resin column with water; terminating the rinsing; eluting the polyphenols fixed on the resin column with aqueous ethanol; collecting the eluate subjected to the vacuum evaporation by adding water regularly to obtain a concentrated juice; evaporating aqueous phase and obtaining the polyphenol. Extraction of polyphenol from Cranberry juice (Vaccinium macrocarpon), comprise eliminating inert substances contained in the juice by diluting concentrated juice in water; fixing polyphenolic substances on a polymer adsorbing material such as styrene/benzene divinyl; rinsing resin column with water; terminating the rinsing of the column when the rate of dry matter in the rinsing liquid having a very low value; eluting the polyphenols fixed on the resin column with aqueous ethanol; collecting the ethanol eluate subjected to the vacuum evaporation by adding water regularly in course of evaporation to obtain a concentrated juice, so that at the end of alcohol evaporation, proanthocyanidin left in pure aqueous medium; evaporating the aqueous phase by high vacuum distillation and finally obtaining the polyphenol concentrate in a powder form containing at least 10% of proanthocyanidin. An independent claim is included for a fine purple to black colored powder containing at least 10% of the proanthocyanidin obtained each time in the process.</p>
申请公布号 EP1913951(A1) 申请公布日期 2008.04.23
申请号 EP20060291611 申请日期 2006.10.17
申请人 PHARMATOKA SAS;GIKA SAS;TOURNAY BIOTECHNOLOGIES 发明人 RENARD, LOIC
分类号 A61K36/45;A23L1/30;A61K31/35;A61P13/00;A61P31/04 主分类号 A61K36/45
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