发明名称 |
SUSTAINED RELEASE PREPARATION AND METHOD FOR PRODUCING THE SAME |
摘要 |
The present invention is to provide a sustained release preparation comprising a drug-containing core substance and a multilayered coating layer covering the core substance, wherein all adjacent layers in the multilayered coating layer contain mutually different hydrophobic organic compound-water-soluble polymer mixtures; and, a method of producing a sustained release preparation, having a multilayered coating layer in which adjacent layers contain different hydrophobic organic compound-water-soluble polymer mixtures, which comprises spray-coating a solution containing a hydrophobic organic compound-water-soluble polymer mixture onto a drug-containing core substance, continuing to spray-coat a solution containing a different hydrophobic organic compound-water-soluble polymer mixture onto the resulting coating layer, and repeating this step.
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申请公布号 |
CA2398555(C) |
申请公布日期 |
2008.04.22 |
申请号 |
CA20012398555 |
申请日期 |
2001.01.26 |
申请人 |
TANABE SEIYAKU CO., LTD. |
发明人 |
IKEGAMI, KENGO;ISHIBASHI, TAKASHI;MIZOBE, MASAKAZU;NAGAO, KEIGO;YOSHINO, HIROYUKI |
分类号 |
A61K9/62;A61K9/28;A61K9/32;A61K9/36;A61K9/42;A61K9/50;A61K9/58 |
主分类号 |
A61K9/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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