发明名称 Indole derivatives as H3 inverse agonists
摘要 The present invention relates to compounds of formula I: wherein X, R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4 </SUP>and R<SUP>5 </SUP>are as defined in the description and claims, and pharmaceutically acceptable salts thereof, to the preparation of such compounds and pharmaceutical compositions containing them. The compounds are useful for the treatment and/or prevention of diseases which are associated with the modulation of H3 receptors.
申请公布号 US7361682(B2) 申请公布日期 2008.04.22
申请号 US20050157093 申请日期 2005.06.20
申请人 HOFFMANN-LA ROCHE INC. 发明人 MCARTHUR SILVIA GATTI;HERTEL CORNELIA;NETTEKOVEN MATTHIAS HEINRICH;RAAB SUSANNE;ROCHE OLIVIER;RODRIGUEZ-SARMIENTO ROSA MARIA;SCHULER FRANZ;PLANCHER JEAN-MARC
分类号 A61K31/55;A61K31/4045;A61K31/454;A61K31/4545;A61K31/5377;A61K31/541;C07D209/42;C07D401/02;C07D401/12;C07D401/14;C07D403/12;C07D403/14;C07D405/14;C07D413/02;C07D417/02 主分类号 A61K31/55
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