| 发明名称 |
PHARMACEUTICAL COMPOSITIONS CONTAINING A SOLID DISPERSION OFA POORLY-SOLUBLE DRUG IN A MATRIX AND A SOLUBILITY-ENHANCING POLYMER |
| 摘要 |
A pharmaceutical composition comprises a dispersion comprising a low- solubility drug and a matrix combined with a concentration-enhancing polymer . At least a major portion of the drug is amorphous in the dispersion. The compositions improve the stability of the drug in the dispersion, and/or the concentration of drug in a use environment.
|
| 申请公布号 |
CA2448864(C) |
申请公布日期 |
2008.04.22 |
| 申请号 |
CA20022448864 |
申请日期 |
2002.05.13 |
| 申请人 |
PFIZER PRODUCTS INC. |
发明人 |
SHANKER, RAVI MYSORE;FRIESEN, DWAYNE THOMAS;KETNER, RODNEY JAMES;LO, JULIAN BELKNAP;BABCOCK, WALTER CHRISTIAN;WEST, JAMES BLAIR;NIGHTINGALE, JAMES ALAN SCHRIVER;CURATOLO, WILLIAM JOHN |
| 分类号 |
A61K47/38;C07D215/42;A61K9/08;A61K9/10;A61K9/14;A61K31/47;A61K47/02;A61K47/10;A61K47/12;A61K47/14;A61K47/18;A61K47/20;A61K47/24;A61K47/26;A61K47/30;A61K47/32;A61K47/34;A61K47/36;A61K47/42;A61K47/44 |
主分类号 |
A61K47/38 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
