METHODS AND COMPOSITIONS FOR INHIBITING NEOPLASTIC CELL GROWTH

摘要

The present invention concerns methods and compositions for inhibiting neoplastic cell growth. In particular, the present invention concerns antitumor compositions and methods for the treatment of tumors. The invention further concerns screen-ing methods for identifying growth inhibitory, e.g., antitumor compounds. The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides o f the present invention fused to heterologous polypep-tide sequences, antibodies which bind to the polypeptides of the present inventio n and to methods for producing the polypeptides of the present invention.