| 摘要 |
FIELD: synthesis of biologically active compounds. ^ SUBSTANCE: invention provides novel biologically active compounds, notably solvate complexes of silicon and titanium glycerates imparting transcutan impermeability to medicaments, which can have utility as ointment base for transdermal therapeutic systems characterized by high penetration ability. There are described solvate complexes of silicon and titanium glycerates depicted by following formula: 2Si(C3H7O3)4.Ti(C3H7O3)4.xC3H8O3, wherein 9<= x<= 30, and hydrogels based thereon, containing water and gel-forming additive at following proportions of components: solvate complexes 48.4-65.2%, gel-forming additive 0.1-0.6%, and water the rest. ^ EFFECT: enlarged resource of transcutan-active materials. ^ 2 cl, 3 tbl, 5 ex |
