| 摘要 |
FIELD: organic chemistry, medicine. ^ SUBSTANCE: invention relates to novel 2-azaspiro[4.6]undecan-3-thiones of the formula (I): wherein X1 and X2 represent in common =S; R1 means hydrogen atom (H); R2 means H; R3 means H, -RQ2; Z means 5-8-membered monocyclic saturated ring bound through a general C-atom with the first azaheterocyclic ring; R8 means (C1-C5)-alkylcarbonyl; Q2 means H, or its pharmaceutically acceptable salts used as an analgesic agent. This allows their using in treatment of chronic inflammatory and/or neuropathic pain. ^ EFFECT: valuable medicinal properties of compounds. ^ 17 cl, 1 tbl, 1 dwg, 8 ex |
