发明名称 |
Powder formulations suitable for inhalation |
摘要 |
A method of making a physically stable and homogenous powdered pharmaceutical composition comprising a tiotropium salt and a physiologically acceptable excipient, the method comprising: (a) suspending the tiotropium salt and the physiologically acceptable excipient in a suspending agent in which the tiotropium salt and the physiologically acceptable excipient are essentially insoluble to obtain a suspension; and (b) removing the suspending agent from the suspension of step (a) to obtain the pharmaceutical composition, the pharmaceutical composition itself, and method of treating respiratory diseases, especially chronic obstructive pulmonary disease and asthma, in a patient in need thereof by administering an effective amount of the pharmaceutical composition to the patient. |
申请公布号 |
HK1078795(A1) |
申请公布日期 |
2008.04.11 |
申请号 |
HK20050110953 |
申请日期 |
2005.12.01 |
申请人 |
BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG |
发明人 |
ROLF BANHOLZER;MANFRED GRAULICH;CHRISTIAN KULINNA;ANDREAS MATHES;HELMUT MEISSNER;PETER SIEGER;PETER SPECHT;MICHAEL TRUNK |
分类号 |
A61K;A61K9/00;A61K9/14;A61K9/72;A61K31/46;A61K47/04;A61K47/10;A61K47/26;A61K47/36;A61P;A61P11/00;A61P11/06 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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