GRP78 AS A PREDICTOR OF RESPONSIVENESS TO THERAPEUTIC AGENTS
摘要
<p>The present application provides methods for detecting, diagnosing, monitoring, predicting responsiveness to therapeutic agents and staging cancer. The present application provides methods and compositions useful for suppression of GRP78 expression or activity in cancer cells to overcome resistance of certain therapeutic agents. The present application also provides methods for predicting whether a subject with cancer is at risk for developing resistance to certain therapeutic agents.</p>
申请公布号
WO2008042508(A1)
申请公布日期
2008.04.10
申请号
WO2007US75960
申请日期
2007.08.15
申请人
UNIVERSITY OF SOUTHERN CALIFORNIA;LEE, AMY, S.;COTE, RICHARD