| 摘要 |
FIELD: organic chemistry, medicine, pharmacy. ^ SUBSTANCE: invention relates to derivatives of 3-hydrozy-2-pyridone represented by the formula (I): wherein R1 means aryl optionally substituted with one or more alkyl group; R2 means hydrogen atom; each R3 and R4 is taken independently of one another from hydrogen atom, alkyl, alkylheteroaryl and aralkyl group; or R3 and R4 in common with nitrogen atom bound with them form heteroaryl or heterocycloaryl substitute optionally substituted with one halogen atom, alkoxy group, aryl, heteroaryl and heterocycloalkyl; R5 and R6 mean hydrogen atom. Also, invention relates to using the compound by any claims among 1-7 for preparing pharmaceutical compositions showing antibacterial properties, and to above said pharmaceutical compositions. Invention provides synthesis of novel compounds possessing useful biological properties, and a pharmaceutical composition based on thereof. ^ EFFECT: valuable medicinal properties of compounds and pharmaceutical composition. ^ 9 cl, 8 ex |
