摘要 |
<p>The present invention relates to compositions and methods that allow the manipulation of the catalytic activity of multi-component nucleic acid complexes. Further, the invention provides methods which use these compositions and methods to create molecular sensors, molecular switches, and/or modulators or propagators of autocatalytic self-replicating cascades and other iterative processes. More particularly, the invention relates to compositions allowing self-assembly of active and inactive multicomponent nucleic acid complexes, methods of making such compositions, and methods for use.</p> |
申请人 |
JOHNSON & JOHNSON RESEARCH PTY LIMITED;TODD, ALISON, VELYIAN;MOKANY, ELISA;BIRKETT, DONALD, JOHN;DOAN, TRAM, BICH;REID, CHRISTOPHER, ROLAND |
发明人 |
TODD, ALISON, VELYIAN;MOKANY, ELISA;BIRKETT, DONALD, JOHN;DOAN, TRAM, BICH;REID, CHRISTOPHER, ROLAND |