发明名称 COMBINED THERAPY USING SUBSTITUTED OXAZOLIDINONES
摘要 FIELD: organic chemistry, medicine, pharmacology. ^ SUBSTANCE: invention relates to a combination used in prophylaxis and/or treatment of thromboembolic diseases. Combination comprises N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)-5-chloro-2-thiophene carboxamide of the formula (I): its pharmaceutically acceptable salts, hydrates or their mixtures and platelet aggregation inhibitor taken in subtherapeutic effective doses. Also, invention relates to a method for preparing this combination and a drug based on thereof. Proposed combination possesses the enhanced effectiveness. ^ EFFECT: improved and valuable medicinal properties of combination. ^ 4 cl, 2 tbl, 176 ex
申请公布号 RU2321407(C2) 申请公布日期 2008.04.10
申请号 RU20040101404 申请日期 2002.06.07
申请人 BAJER KHEL'SKER AG 发明人 SHTRAUB ALEKSANDER;LAMPE TOMAS;PERNERSHTORFER DZHOZEF;PERTSBORN EHLIZABET;POL'MANN JENS;RERIG SJUZANNE;SHLEMMER KARL-KHAJNTS
分类号 A61K31/5377;C07D413/12;A61K31/421;A61K31/422;A61K31/423;A61K31/427;A61K31/428;A61K31/435;A61K31/4365;A61K31/4439;A61K31/444;A61K31/454;A61K31/496;A61K31/535;A61K31/5355;A61K31/538;A61K31/5383;A61K31/541;A61K45/00;A61K45/06;A61P7/02;A61P7/12;A61P9/00;A61P9/04;A61P9/08;A61P9/10;A61P43/00;C07D413/14;C07D417/14;C07D495/04;C07D498/04 主分类号 A61K31/5377
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