发明名称 Substituted isoquinoline-1,3(2H,4H)-diones, 1-thioxo-1,4-dihydro-2H-isoquinoline-3-ones and 1,4-dihydro-3 (2H)-isoquinolones and methods of use thereof
摘要 This invention provides compounds of Formula (I), having the structure where G<SUP>1</SUP>, G<SUP>2</SUP>, G<SUP>3</SUP>, G<SUP>4</SUP>, A<SUP>1</SUP>, A<SUP>2</SUP>, Y<SUP>1</SUP>, Y<SUP>2</SUP>, L<SUP>1</SUP>, Z, e and f are defined herein, or a pharmaceutically acceptable salt thereof, which are useful for treating or preventing cancer.
申请公布号 US2008085890(A1) 申请公布日期 2008.04.10
申请号 US20070728897 申请日期 2007.03.26
申请人 WYETH 发明人 TSOU HWEI-RU;AYRAL-KALOUSTIAN SEMIRAMIS;BIRNBERG GARY H.;FLOYD MIDDLETON B.;KAPLAN JOSHUA;KUTTERER KRISTINA M.;LIU XIAOXIANG;NILAKANTAN RAMASWAMY;OTTENG MERCY A.;TANG ZHILIAN;ZASK ARIE;TRAN TRITIN;MAYER SCOTT C.;BANKER ANNETTE L.;REICH MARVIN
分类号 A61K31/55;A61K31/47;A61K31/496;A61K31/497;A61K31/501;A61K31/502;A61K31/506;A61K31/5377;A61K31/541;A61P1/00;A61P3/10;A61P9/00;A61P11/00;A61P17/06;A61P19/02;A61P31/10;A61P31/12;A61P35/00;C07D217/00;C07D223/02;C07D237/02;C07D237/26;C07D239/02;C07D241/02;C07D295/00 主分类号 A61K31/55
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