发明名称 |
FORMULATION FOR DELIVERY OF IMMUNE RESPONSE MODIFIERS |
摘要 |
The present invention provides pharmaceutical compositions that include an IRM-PEG complex and an antigen, formulated together in a thermoresponsive gel. In another aspect, the present invention also provides a method of eliciting an antigen-specific immune response in a subject. Generally, the method includes administering to the subject a pharmaceutical composition comprising an IRM-PEG complex and an antigen, formulated together in a thermoresponsive gel, in an amount effective to generate an immune response in the subject against the antigen. In yet another aspect, the present invention also provides a method of treating a condition in a subject. Generally, the method includes administering to the subject a pharmaceutical composition comprising an IRM-PEG complex and an antigen, formulated together in a thermoresponsive gel, in an amount effective to ameliorate at least one symptom or clinical sign of the condition. |
申请公布号 |
WO2007149802(A3) |
申请公布日期 |
2008.04.10 |
申请号 |
WO2007US71433 |
申请日期 |
2007.06.18 |
申请人 |
3M INNOVATIVE PROPERTIES COMPANY;GORSKI, KEVIN S.;ORTIZ, RONNIE;STOESZ, JAMES D.;ZARRAGA, ISIDRO ANGELO E. |
发明人 |
GORSKI, KEVIN S.;ORTIZ, RONNIE;STOESZ, JAMES D.;ZARRAGA, ISIDRO ANGELO E. |
分类号 |
A61K9/06;A61K39/39 |
主分类号 |
A61K9/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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