发明名称 |
SELF-PRESERVED AQUEOUS PHARMACEUTICAL COMPOSITIONS |
摘要 |
The use of a borate/polyol and zinc system to enhance the antimicrobial a ctivity of multi-dose pharmaceutical compositions is described. The composit ions do not require a conventional anti-microbial preservative and therefore are referred to as being 'self-preserved'. The compositions possess suffici ent antimicrobial activity to satisfy the preservative efficacy requirements of the USP for aqueous ophthalmic compositions.
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申请公布号 |
CA2663817(A1) |
申请公布日期 |
2008.04.10 |
申请号 |
CA20072663817 |
申请日期 |
2007.09.20 |
申请人 |
ALCON RESEARCH, LTD. |
发明人 |
KEITH, DAVID J.;CHOWHAN, MASOOD A. |
分类号 |
A61K9/00;A61K31/00;A61K47/02;A61K47/10 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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地址 |
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