摘要 |
<P>PROBLEM TO BE SOLVED: To attain long-term release rate profile to pseudoephedrine component for ≥12 hr, preferably exceeding 16 hr while keeping delivery of effective once daily dosage of desloratadine. <P>SOLUTION: This film-coated, extended release solid oral dosage composition comprises (a) a core comprising an effective amount of pseudoephedrine or pharmaceutically acceptable salt thereof, and (b) a film coating uniformly covering the core and comprising an effective amount of desloratadine. <P>COPYRIGHT: (C)2008,JPO&INPIT |