发明名称 CYCLIC MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY
摘要 <p>The present application describes modulators of MIP-1a or CCR-1 of formula (I) or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein n, ring A, T, V, X, R&lt;SUB&gt;1&lt;/SUB&gt;, R&lt;SUB&gt;2&lt;/SUB&gt; and R&lt;SUB&gt;8&lt;/SUB&gt;, are defined herein. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis and transplant rejection using modulators of formula (I) are disclosed.</p>
申请公布号 WO2008042926(A1) 申请公布日期 2008.04.10
申请号 WO2007US80240 申请日期 2007.10.03
申请人 BRISTOL-MYERS SQUIBB COMPANY;CARTER, PERCY H. 发明人 CARTER, PERCY H.
分类号 C07D211/22;A61K31/445;A61P19/02;A61P29/00;A61P37/08 主分类号 C07D211/22
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