PHARMACEUTICAL USE OF SUBSTITUTED PIPERIDINE CARBOXAMIDES
摘要
A novel class of compounds of the general formula (I) and (Ia), their use in therapy, pharmaceutical compositions comprising the compounds, as well as their use in the manufacture of medicaments are described. The present compounds modulate the activity of 11ß- hydroxysteroid dehydrogenase type 1 (11ßHSD1) and are accordingly useful in the treatment of diseases in which such a modulation is beneficial, e.g. the metabolic syndrome.
申请公布号
WO2007144394(A3)
申请公布日期
2008.04.10
申请号
WO2007EP55865
申请日期
2007.06.14
申请人
NOVO NORDISK A/S;KILBURN, JOHN, PAUL;KAMPEN, GITA, CAMILLA, TEJLGAARD;ANDERSEN, HENRIK, SUNE