发明名称 BIOMATERIAL, METHOD FOR ITS PREPARING AND ITS USING, MEDICINAL AGENT, IMPLANT AND INSERT
摘要 FIELD: medicine, polymeric materials, pharmacy. ^ SUBSTANCE: invention describes biomaterial as a deposit comprising at least one suitable anion-active polymeric water-soluble component and amphiphilic component of ammonium type comprising a cationic surfactant. Deposit is prepared in the following steps: (1) contacting anion-active polymeric component and cyclodextrin component in aqueous medium, and (2) addition of the above said amphiphilic component of ammonium type to mixture prepared in the step (1) wherein components are taken in amounts providing formation of above said deposit. Biomaterial is used for preparing a depot-composition with regulated release and acceptable for prolonged feeding pharmaceutical substances. Also, invention describes a medicinal agent comprising biomaterial and representing a sheet material or film for closing and healing wounds, or surgery thread, and medicinal implant, or insert comprising the preliminary molded biomaterial. ^ EFFECT: improved preparing method, valuable properties of material. ^ 27 cl, 34 ex
申请公布号 RU2321597(C2) 申请公布日期 2008.04.10
申请号 RU20040133887 申请日期 2003.04.17
申请人 NOVARTIS AG 发明人 SENTE LAJOSH;SEJTLI JOZHEF;KISH D'ERD' LAJOSH;SHOKH KRISTIAN
分类号 A61K47/48;C08B37/00;A23L35/00;A61K9/00;A61K9/12;A61K9/20;A61K9/70;A61K31/715;A61K31/724;A61K31/726;A61K31/78;A61K47/18;A61K47/36;A61K47/40;A61L27/20;A61L27/54;C08L5/00;C08L101/16 主分类号 A61K47/48
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