发明名称 |
Process for the preparation of memantine and its hydrochloric acid salt form |
摘要 |
The present invention relates to the synthesis of 1-amino-3,5-dimethyladamantane ("memantine") and its hydrochloric acid salt form. In particular a new intermediate (N-chloro-acetylamino-3,5-dimethyladamantane) for the synthesis of memantine as well as a new process for the preparation of memantine and its hydrochloric acid salt form using said intermediate is disclosed.
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申请公布号 |
EP1908748(A1) |
申请公布日期 |
2008.04.09 |
申请号 |
EP20060020944 |
申请日期 |
2006.10.05 |
申请人 |
KRKA |
发明人 |
TIHI, JAROSLAV;MELEH, MARIJA;VRECER, FRANC;ZUPET, ROK;PUCELJ, JOZE;PELKO, MITJA |
分类号 |
C07C233/06;C07C209/62;C07C211/38 |
主分类号 |
C07C233/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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