Novel G protein-coupled receptor proteins

摘要

This invention belongs to the genetic engineering field, and provides the novel G protein-coupled receptor family protein SREB3 expressed in the central nervous system, genes coding for this protein, screening methods using this protein and so on. As one of the methods for obtaining the G protein-coupled receptor proteins of the present invention, RT-PCR is carried out using mRNA extracted from human or rat brain tissue or brain-derived cells as the template and using two primers interposing the entire portion or a part of the G protein-coupled receptor protein translation region, thereby obtaining cDNA corresponding to the G protein-coupled receptor protein or a part thereof, and the cDNA is integrated into an appropriate expression vector and expressed in a host cell.