| 发明名称 |
AT1-RECEPTOR ANTAGONISTS FOR PREVENTING AND TREATING POSTISCHEMIC RENAL FAILURE AND FOR PROTECTING ISCHEMIC KIDNEYS |
| 摘要 |
AT1-receptor antagonists and particularly the compound (S)-N-(1-carboxy-2-methylprop-1-yl)-N--pentanoyl-N-[2' (1H-tetrazol-5- yl)biphenyl--4-yl-methyl]amine (valsartan) of formula (I) or a salt thereof, in particular a pharmaceutically acceptable salt thereof, can be used for treating (acute and chronic) postischemic renal failure and for protecting the ischemic kidney.
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| 申请公布号 |
CA2232663(C) |
申请公布日期 |
2008.04.08 |
| 申请号 |
CA19962232663 |
申请日期 |
1996.09.24 |
| 申请人 |
NOVARTIS AG |
发明人 |
HUMKE, ULRICH |
| 分类号 |
A61K31/41;C07D401/10;A61K31/00;A61K31/415;A61K31/4164;A61K31/4174;A61K31/4178;A61K31/4184;A61K31/4188;A61K31/437;A61K31/44;A61K31/4427;A61K31/443;A61K31/4433;A61K31/4439;A61K31/455;A61K31/47;A61K31/4709;A61K31/472;A61K31/4725;A61K45/00;A61P9/10;A61P13/00;A61P13/12;C07D257/04;C07D401/14;C07D403/10;C07D405/06;C07D409/06;C07D471/04 |
主分类号 |
A61K31/41 |
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