发明名称 |
Use of VEGF antagonists for the treatment of malignant gliomas |
摘要 |
Methods for treating a human patient suffering from a brain tumor, including glioblastoma, by administering an effective amount of a vascular endothelial growth factor (VEGF) inhibitor to the human patient. The VEGF inhibitor is a VEGF antagonist protein comprising a dimeric protein having two fusion polypeptides having the sequence of SEQ ID NO:2. |
申请公布号 |
US7354582(B2) |
申请公布日期 |
2008.04.08 |
申请号 |
US20060373462 |
申请日期 |
2006.03.10 |
申请人 |
REGENERON PHARMACEUTICALS, INC. |
发明人 |
YUNG W. K. ALFRED;GOMEZ-MANZANO CANDELARIA;FUEYO JUAN;CEDARBAUM JESSE M.;HOLASH JOCELYN |
分类号 |
A61K38/18;C07K14/71;C12N15/62 |
主分类号 |
A61K38/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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