发明名称 Isolated nucleic acids and polypeptides associated with glucose homeostasis disorders and method of detecting the same
摘要 An isolated and substantially pure nucleic acid sequence located between D20S119 and D20S178 on human chromosome 20q13, the nucleic acid sequence including: a nucleic acid sequence coding for a glucose transporting protein and having the sequence shown in SEQ ID NO: 1; or a nucleic acid sequence having at least 70% sequence identity with the nucleic acid sequence shown in SEQ ID NO: 1. The disclosed nucleic acid sequences map to a locus associated with human Type II diabetes mellitus and, therefore, therapeutic and diagnostic screening methods, which accommodate naturally and artificially occurring polymorphisms, are also disclosed.
申请公布号 US7355023(B2) 申请公布日期 2008.04.08
申请号 US20020328198 申请日期 2002.12.23
申请人 DUKE UNIVERSITY 发明人 CHEN Y. T.;MCVIE-WYLIE ALISON J.
分类号 C07H21/04;A61K31/70;C07K14/62;C12N15/63;C12Q1/68;G01N33/564 主分类号 C07H21/04
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