NUCLEIC ACID PURIFICATION METHOD

摘要

Disclosed is a process for separating and/or purifying a nucleic acid by elution of the nucleic acid from anion exchange resins under conditions of h igh salt concentration and the presence in the eluant of an additive compris ing guanidine, or a guanidine-like derivative. The process allows high recov ery of nucleic acids from anion exchange resins without impairing the nuclei c acid stability as compared with conventional ion exchange chromatographic procedures.