发明名称 PROCESS FOR THE PREPARATION OF ABACAVIR
摘要 <p>Process for removal of the amino protective group of a N-acylated {(1S,4R)-4- [2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-cyclopent-2-enyl}methanol of formula (II) where R = H or a (C<SUB>1</SUB>-C<SUB>4</SUB>)-alkyl, using an inorganic base in a mixture of water and alcohol, to yield abacavir or its salts. The process proceeds very fast and the product can be obtained in high yield and purity.</p>
申请公布号 WO2008037760(A1) 申请公布日期 2008.04.03
申请号 WO2007EP60249 申请日期 2007.09.27
申请人 ESTEVE QUIMICA, S.A.;MEDRANO RUPEREZ, JORGE;CAMPON PARDO, JULIO;ELIAS RIUS, LAIA;BERENGUER MAIMO, RAMON 发明人 MEDRANO RUPEREZ, JORGE;CAMPON PARDO, JULIO;ELIAS RIUS, LAIA;BERENGUER MAIMO, RAMON
分类号 C07D473/16 主分类号 C07D473/16
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