| 摘要 |
The invention is directed to a method for oral administration of a liquid containing an active substance to a subject for improved absorption into th e subject's bloodstream includes the steps of providing a delivery device co ntaining the liquid and having a mouthpiece for directing the liquid in a de fined direction during delivery; directing the mouthpiece toward a localized area of the subject's mouth being especially suitable for increased uptake and faster onset of action of the active substance relative to other areas o f and/or the whole mouth; and delivering a measured amount of the liquid dir ectly to the localized area using the delivery device, and a spray device fo r administering an active substance to the oral cavity of a subject that inc ludes a container capable of holding a liquid containing an active substance , and a mouthpiece being constructed to dispense the liquid containing the s ubstance in a defined direction and directly to a localized area of a subjec t's mouth, the localized area being the oral vestibule. |
