| 摘要 |
Provided are nucleotide-label conjugates and related compounds in which a label, such as a fluorescent dye, is linked to a nucleobase directly or indirectly by a linker. In some embodiments, the linker comprises a backbone comprising at least one imidazolium moiety. Such conjugates are useful, for example, in primer extension methods and related techniques, and in methods that involve electrophoresis of polynucleotides, such as certain DNA sequencing techniques. Methods, kits, and compositions are also disclosed. |
