| 摘要 |
PROBLEM TO BE SOLVED: To provide a marker gene which is useful in differential diagnosis of intrahepatic cholangiocarcinoma (ICC) and a method of differential diagnosis of the intrahepatic cholangiocarcinoma (ICC) using the marker gene. SOLUTION: The reagent for detecting intrahepatic cholangiocarcinoma contains a nucleotide comprising a base sequence of one gene or at least two genes selected from among a group comprising four kinds of genes: (1) insulin-like growth factor-binding protein 5 (IGFBP5), (2) Claudin4 (CLDN4), (3) PDZ and LIM domain 7 (PDLIM7), and (4) Biglycan (BGN), excluding Claudin4 or a nucleotide that contains a partial sequence thereof. COPYRIGHT: (C)2008,JPO&INPIT
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