发明名称 |
COMPOSITIONS AND METHODS FOR ENHANCING NEURONAL PLASTICITY AND REGENERATION |
摘要 |
The present invention relates PirB expression and function in nervous tissue. PirB expressed in neurons acts to restrict plasticity of neural circuits, and/or, restrict competition between circuits with different activity patterns or levels, for cortical representation. Thus, the present invention relates to methods of increasing nervous system plasticity and associated disorders and diseases in a subject comprising administering to the subject an agent which modulates the activity, signal transduction or expression of PirB in neurons of the subject. |
申请公布号 |
WO2007092165(A3) |
申请公布日期 |
2008.04.03 |
申请号 |
WO2007US02009 |
申请日期 |
2007.01.23 |
申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE;SHATZ, CARLA;SYKEN, JOSHUA |
发明人 |
SHATZ, CARLA;SYKEN, JOSHUA |
分类号 |
A61K38/00;A61K39/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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