ASSESSMENT OF THE EFFECTS OF TOPICAL ADMINISTRATION OF CHEMODENERVATING PHARMACEUTICALS

摘要

The present invention provides methods for assessing the activity of topically administered chemodenervating agents. In some embodiments, methods for assessing the activity of topically administered chemodenervating agents involve determining the extent of inhibition of acetylcholine release near the site of administration. In some embodiments, methods for assessing activity of topically administered chemodenervating agents involve observing a reflex motion of a limb of a subject.