ORGANIC-INORGANIC HYBRID CHIRAL SORBENT AND PROCESS FOR THE PREPARATION THEREOF

摘要

The present invention provides an organic-inorganic hybrid chiral sorbent for chiral resolution of various racemic compounds viz. racemic mandelic ac id, 2- phenyl propionic acid, diethyl tartrate, 2,2'-dihydroxy-1,1 '-binapht halene (BINOL) and cyano chromene oxide with excellent chiral separation (en antiomeric excess, 99 %) in case of mandelic acid under medium pressure colu mn chromatography. These optically pure enantiomers find applications as int ermediates in pharmaceutical industries.