摘要 |
A method of improving the physical properties of an solid oral dosage form, especially a tablet, uses an external lubricant during the compaction process. The solid oral dosage form comprises a pharmacologically active agent, for example a protein or polypeptide, and a delivery agent. Tablet properties, such as hardness, disintegration time and dissolution, are improved using the method. |
申请人 |
NOVARTIS AG;GHOSH, ANASUYA, ASHOK;JOSHI, YATINDRA;LI, SHOUFENG;ROYCE, ALAN, EDWARD;RUEGGER, COLLEEN |
发明人 |
GHOSH, ANASUYA, ASHOK;JOSHI, YATINDRA;LI, SHOUFENG;ROYCE, ALAN, EDWARD;RUEGGER, COLLEEN |